代表論文等

著書
1)齋藤 繁
「脳神経外科手術の麻酔」日本麻酔科学会 教育委員会・安全委員会 編「JSAリフレッシャーコース」
メディカル・サイエンスインターナショナル、東京 2006年 312-319
2)齋藤 繁
「尿崩症」稲田英一 編「麻酔科診療プラクティス?周術期の輸液・輸血療法」 文光堂、東京 2005年 248-249
3)齋藤 繁
「高山病」日本山岳会医療委員会 編「山の救急医療ハンドブック」山と渓谷社、東京、2005年、100-103
4)齋藤 繁
「神経ブロックと自家骨髄細胞移植による慢性動脈閉塞症の治療」後藤文夫・並木昭義・島田康宏 編「麻酔科の新しい流れ」先端医療技術研究所、東京、2005年、305-308

欧文単著・筆頭著者
1)Saito S, Nishikawa K, Obata H, Goto F.

Combined use of autologous bone marrow transplantation and hyperbaric oxygen therapy for the patients with thromboangiitis obliterans. Angiology 58:429-34,2007
2)Saito S.
Neurotoxicity of local anesthetics: effects on growing neurites and growth cones.
J Anesth.21:535-7,2007
3) Saito S, Nishihara F, Akihiro T, Nishikawa K, Obata H, Goto F, Yuki N. Landiolol and esmolol prevent tachycardia without altering cerebral blood flow. Can J Anesth. 52:1027-34, 2005
4) Saito S, Tanobe K, Yamada M, Nishihara F. Relationship between arterial oxygen saturation and heart rate variability at high altitudes. Am J Emerg Med.;23: 8-12. 2005

欧文共著
1)Ide M, Kadoi Y, Saito S, Takahashi K, Sawano Y, Miyazaki M, Shimada H.
Effects of landiolol on left ventricular function during electroconvulsive therapy: a transthoracic echocardiographic study J Anesthesia 24:81-95.2010

2)kadoi Y, Horiuchi T, Uchida S, Saito S, Satoh J, Takahashi K.
Young age and the presence of hypertension attenuate the heart rate-reducing effect of landiolol during emergency from anesthesia and tracheal extubation.
Journal of Japan Society for Clinical Anesthesia 30:237-46.2010
3) Kakeda T, OginoY, Moriya F, Saito S.
Sweet taste-induced analgesia: an fMRI study.
Neuroreport [Epub Mar 8].2010

4)Nazeer A, Saito S, Sayed S, Hassan L, Askar F, Al-Jahdari W, Seki T, Hideaki O
Normal glucose enhances neuronal regeneration after lidocaine-induced injury.
Br J Anaesth [Epub Mar 1].2010
5)Oshima K, Kunimoto F, Hinohara H, Ohkawa M, Mita N, Tajima Y, Saito S.
Extracorporeal membrane oxygenation for respiratory failure: comparison of venovenous versus venoarterial bypass.
Surg Today [Epub Feb 24.].2010
6)Kadoi Y, Saito S.
Possible indications of beta-blockers in the perioperative period other than prevention of cardiac ischemia.
J Anesthesia 24:81-95 .2010
7)Al-Jahdari WS, Suzuki Y, Yoshida Y, Hamada N, Shirai K, Noda SE, Funayama T, Sakashita T, Kobayashi Y, Saito S, Goto F, Nakano T. The radiobiological effectiveness of carbon-ion beams on growing neurons.
Int J Radiat Biol. 85:700-9.2009
8) Ito N, Obata H, Saito S.
Spinal microglial expression and mechanical hypersensitivity in a postoperative pain model: comparison with a neuropathic pain model. Anesthesiology 111:640-8.2009
9) Kadoi Y, Kawauchi C, Ide M, Saito S, Mizutani A.
Differential increases in blood flow velocity in the middle cerebral artery after tourniquet deflation during sevoflurane, isoflurane or propofol anesthesia
Anaesth Intensive Care 37:598-603.2009
10) Kadoi Y, Kawauchi C, Saito S, Takahashi K.
The comparative effects of equipotent Bispectral Index dosages of propofol versus sevoflurane on cerebrovascular carbon dioxide reactivity in elderly patients.
J Clinical Anesth 21:173-7.2009
11) Koizuka S, Saito S, Sekimoto K, Tobe M, Koyama Y, Obata H.
Percutaneous radio-frequency thermocoagulation of the Gasserian ganglion guided by high speed real-time CT fluoroscopy.
Neuroradiology 51:563-6.2009
12) Kubo K, Nishikawa K, Hardy-Yamada M, Ishizeki J, Yanagawa Y, Saito S.
Altered responses to propofol, but not ketamine, in mice deficient in the 65-kilodalton isoform of glutamate decarboxylase.
Journal of Pharmacology and Experimental Therapeutics 329:592-9.2009
13) Kubo K, Nishikawa K, Ishizeki J, Hardy-Yamada M, Yanagawa Y, Saito S.
Thermal hyperalgesia via supraspinal mechanisms in mice lacking glutamate decarboxylase (GAD) 65.
Journal of Pharmacology and Experimental Therapeutics 331:162-9.2009
14) Kuroda M, Matsuoka H, Aso C, Iriuchijima N, Miyoshi S, Kadoi Y, Saito S.
Transesophageal echocardiography is useful for an intraoperative diagnosis of pulmonary artery catheter entrapment.
Anesth Analg 109:1416-8.2009
15) Matsumoto N, Tomioka A, Sato T, Kawasaki M, Kadoi Y, Saito S.
Relationship between cardiac output and onset of succinylcholine chloride action in electroconvulsive therapy patients.
J ECT 25:246-9.2009
16) Miyazaki M, Kadoi Y, Saito S.
Effects of landiolol, a short-acting beta-1 blocker, on hemodynamic variables during emergence from anesthesia and tracheal extubation in elderly patients with and without hypertension.
J Anesthesia 23:483-8.2009
17) Nakajima K, Obata H, Ito N, Goto F, Saito S.
The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats.
Eur J Pain 13:441-7.2009
18) Nishikawa K, Matsuoka H, Saito S.
Tracheal intubation with the PENTAX-AWS (Airway scope) reduces changes of hemodynamic responses and bispectral index scores compared to the Macintosh laryngoscope.
Journal of Neurosurgical Anesthesiology 21:292-6.2009
19) Kadoi Y, Saito S.

Anesthetic considerations for electroconvulsive therapy -Especially hemodynamic and respiratory management.
Current Psychiatry Reviews 5:276-286.2009
20) Kadoi Y, Saito S.
Beta-blockers in the perioperative period: are there indications other than prevention of cardiac ischemia?
Current Drug Targets 10:842-849.2009
21)Kadoi Y, Saito S .

A novel ultra-short-acting beta-blocker, Landiolol: effective use during electroconvulsive therapy and tracheal intubation.
Beta-Blockers: New Research, Nova Science Publishers, Inc. New York, Endo M and Matsumoto N, editors, p55-73 .2009
22)Al-Jahdari WS, Suzuki Y, Yoshida Y, Noda SE, Shirai K, Saito S, Goto F, Nakano T.
Growth cone collapse and neurite retractions: an approach to examine X-irradiation affects on neuron cells.
J Radiat Res (Tokyo) 49:481-9 .2009 23)Kubo K, Nishikawa K, Hardy-Yamada M, Yanagawa Y, Saito S.
Altered responses to propofol, but not ketamine, in mice deficient in the 65-kilodalton isoform of glutamate decarboxylase.
J Pharmacol Exp Ther 329:592-9.2009
24)Nakajima K, Obata H, Ito N, Goto F, Saito S.

The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats.
Eur J Pain 13:441-7.2009
25)Sakaue H, Suto T, Kimura M, Narahara S, Sato T, Tobe M, Aso C, Kakinuma T, Hardy-Yamada M, Saito S.
Oxygen inhalation using an oxygen concentrator in a low-pressure environment outside of a hospital
Am J Emerg Med. 26:981-984.2008
26) Oshima K, Kunimoto F, Hinohara H, Ohkawa M, Saito S.
The effect of a temporary inferior vena cava filter in the treatment of deep vein thrombosis in critically-ill patients.
Int Heart J 49:713-21. 2008

27)Kadoi Y, Saito S, Takahashi K.

The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke.
J Anesth 22:135-9.2008
28) Kadoi Y, Hinohara H, Kunimoto F, Saito S.
Effects of the cannabinoid antagonist AM281 on systemic hemodynamics and mortality rate in streptozotocin- induced diabetic rats with endotoxic shock − Comparison between non-diabetic and diabetic rats
Acta Anaesthesiol. Scand 52:664-72.2008
29) Kadoi Y, Saito S, Kawauchi C, Hinohara H, Kunimoto F.
Comparative effects of propofol versus dexmedetomidine on cerebrovascular carbon dioxide reactivity in patients with septic shock.
Br. J Anesth. 100:224-9.2008
30) Kuroda M, Yoshikawa D, Koizuka S, Nishikawa K, Saito S, Goto F.
The effects of isoflurane on adrenomedullin-induced hemodynamic responses in pithed rats.
Eur J Anesthesiol 13:1-6 .2008
31)Kadoi Y, Saito S, Kawauchi C, Hinohara H, Kunimoto F

Comparative effects of propofol versus dexmedetomidine on cerebrovascular carbon dioxide reactivity in patients with septic shock.
Br. J Anesth.100:224-9,2008
32)Ishizeki J, Nishikawa K, Kubo K, Saito S, Goto F

Amnestic concentrations of sevoflurane inhibit synaptic plasticity ofhippocampal CA1 neurons through gamma-aminobutyric acid-mediated mechanisms.
Anesthesiology. 108:447-56,2008
33)Suto, T, Hardy-Yamada M, Kakinuma T, Miyazaki M, Shimada H, Sato J, Saito S.
A case report of a glomus tumour with severe local pain
The Pain Clinic19:41-2,2007
34)Nishikawa K, Hagiwara R, Nakamura K, Ishizeki J, Kubo K, Saito S, Goto F.
The effects of the extent of spinal block on the BIS score and regional cerebral oxygen saturation in elderly patients: A prospective, randomized, and double-blinded study.
J Clin Monit Comput.21:109-14,2007
35) Nishikawa K, Yokoyama N, Saito S, Goto F.
Comparison of effects of rapid colloid loading before and after spinal anesthesia on maternal hemodynamics and neonatal outcomes in cesarean section.
J Clin Monit Comput.21:125-9,2007
36) Obata H, Ito N, Sasaki M, Saito S, Goto F.
Possible involvement of spinal noradrenergic mechanisms in the antiallodynic effect of intrathecally administered 5-HT2C receptor agonists in the rats with peripheral nerve injury.
Eur J Pharmacol.567:89-94,2007
37) Ogino Y, Nemoto H, Inui K, Saito S, Kakigi R, Goto F
Inner experienceof pain: imagination of pain while viewing images showing painfulevents forms subjective pain representation in human brain.
Cerebral Cortex17:1139-46 ,2007
38) Kadoi Y, Saito S, Takahashi K
The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with hypertension. Acta Anaesthesiol. Scand.51:1382-7,2007

39) Sekimoto K, Saito S, Goto F Tetracaine at a small concentration delayed nerve growth without destroying neuritis and growth cones. Anesth Analg 103:608-614,2006
40) Al-Jahdari W, Saito S, Goto F Neurotoxicity of propofol on growth cones and neuritis of growing neurons in vitro. Can J Anesthesia 53:1078-1085,2006
41) Ogino Y, Nemoto H, Inui K, Saito S, Kakigi R, Goto F. Inner experience of pain: Imagination of pain while viewing images showing painful events forms subjective pain representation in human brain. Cereb Cortex.; [Epub ahead of print] 2006
42) Kadoi Y, Takahashi K, Saito S, Goto F The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with diabetes mellitus. Anesth Analg 103:168-72, 2006
43) Sekimoto K, Nishikawa K, Ishizeki J, Kubo K, Saito S, Goto F. The effects of volatile anesthetics on intraoperative monitoring of myogenic motor-evoked potentials to transcranial electrical stimulation and on partial neuromuscular blockade during
propofol/fentanyl/nitrous oxide anesthesia in humans. J Neurosurg Anesthesiol 18:106-11, 2006
44) Sasaki M, Obata H, Kawahara K, Saito S, Goto F Peripheral 5-HT(2A) receptor antagonism attenuates primary thermal hyperalgesia and secondary mechanical allodynia after thermal injury in rats. Pain 122:130-6, 2006
45) Takizawa E, Takizawa D, Hiraoka H, Saito S, Goto F. Disposition and pharmacodynamics of propofol during isovolaemic haemorrhage followed by crystalloid resuscitation in humans. Br J Clin Pharmacol 61:256-61, 2006
46) Sakurazawa S, Saito S*, Yamada M, Nishihara F, Goto F. Carbon dioxide exhalation temporarily increases during electroconvulsive therapy. J Anesth 20:68-70, 2006
47) Kadoi Y, Hinohara H, Kunimoto F, Saito S, Goto F. Fentanyl-induced hemodynamic changes after esophagectomy or cardiac surgery. J Clin Anesth 17:598-603, 2005
48) Kadoi Y, Hinohara H, Kunimoto F, Saito S, Goto F. Cannabinoid antagonist AM 281 reduces mortality rate and neurologic dysfunction after cecal ligation and puncture in rats. Crit Care Med 33:2629-36, 2005
49) Saito S. Anesthesia management for electroconvulsive therapy: hemodynamic and respiratory management. J Anesth. 19:142-9, 2005 (review).
国際学会
1) Saito S Multimodal approach for ischemic limb, Neurotoxic effects of local anesthetics, Nerve blocks guided by CT fluoroscopy. 10th annual conference of Alexandria Society of Anesthesia and Intensive Care, Alexandria, 2006 (symposist)
国内学会(講演・シンポジストのみ)
1) 齋藤 繁 「神経因性疼痛治療薬への新たなる挑戦」 日本薬理学会 第80回年会、名古屋2007、(シンポジスト)
2) 齋藤 繁 「低酸素環境への挑戦:高齢登山者エベレスト登頂を支える技術とは」 日本医療ガス学会 第10回学術大会、横浜2006、(講演)
3) 齋藤 繁 「局所麻酔薬の神経再生に及ぼす効果と神経ブロックへの応用」 日本学術会議 脳のシンポジウム、前橋 2006、(シンポジスト)

受賞歴、研究費等
科学研究費 取得状況 (過去10年間分)
(1) 平成17-19年度:基盤研究C(2) <研究代表者>
(2) 平成14-16年度:基盤研究B(2)<代表者 後藤文夫(分担)>
(3) 平成13-15年度:基盤研究C(2)<研究代表者>
(4) 平成11-12年度:奨励研究A <研究代表者>
(5) 平成10-12年度:基盤研究B(2)<代表者 後藤文夫(分担)>
北関東医学会奨励賞2004年10月8日